David T Davies

5PUBLICATIONS
24CO-AUTHORS
Plant and fungus systematics and taxonomyPharmacogenomicsInfectious agentsMedical infection agents (incl. prions)
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Publications (5)

|Jan 20, 2023
Chemical Optimization of Selective Pseudomonas aeruginosa LasB Elastase Inhibitors and Their Impact on LasB-Mediated Activation of IL-1β in Cellular and Animal Infection Models.

Martin J Everett, David T Davies, Simon Leiris

|Mar 31, 2021
Designing Inhibitors of β-Lactamase Enzymes to Overcome Carbapenem Resistance in Gram-Negative Bacteria.

David T Davies, Martin Everett

|Dec 11, 2020
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.

David T Davies, Simon Leiris, Magdalena Zalacain

|Aug 14, 2020
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.

David T Davies, Simon Leiris, Nicolas Sprynski

|Nov 15, 2018
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.

Simon Leiris, Alicia Coelho, Jérôme Castandet

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Frequent Collaborators

5 joint publications

Martin J Everett

4 joint publications

Marc Lemonnier

3 joint publications

Jérôme M Castandet

3 joint publications

Thomas David Pallin