Manuela Benvenuti

8PUBLICATIONS
29CO-AUTHORS
Medical bacteriologyInfectious agentsMedical infection agents (incl. prions)Cheminformatics and quantitative structure-activity relationships
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Journal

Publications (8)

|Nov 30, 2022
Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates.

Alice Legru, Federica Verdirosa, Yen Vo-Hoang

|Dec 11, 2020
Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii.

David T Davies, Simon Leiris, Magdalena Zalacain

|Aug 14, 2020
ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae.

David T Davies, Simon Leiris, Nicolas Sprynski

|Dec 25, 2019
VNRX-5133 (Taniborbactam), a Broad-Spectrum Inhibitor of Serine- and Metallo-β-Lactamases, Restores Activity of Cefepime in Enterobacterales and Pseudomonas aeruginosa.

Jodie C Hamrick, Jean-Denis Docquier, Tsuyoshi Uehara

|Nov 26, 2019
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections.

Bin Liu, Robert E Lee Trout, Guo-Hua Chu

|Nov 15, 2018
SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model.

Simon Leiris, Alicia Coelho, Jérôme Castandet

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Frequent Collaborators

8 joint publications

Cecilia Pozzi

8 joint publications

Stefano Mangani

7 joint publications

Jean-Denis Docquier

4 joint publications

Filomena De Luca