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Timothy J Miles

8PUBLICATIONS

35CO-AUTHORS

ChemotherapyCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsBiologically active moleculesBiomolecular modelling and design

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Publications (8)

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|Dec 13, 2023

Short-course combination treatment for experimental chronic Chagas disease.

Silvia González, Richard J Wall, John Thomas

|Jul 28, 2023

Structure-Guided Design and Synthesis of a Pyridazinone Series of <i>Trypanosoma cruzi</i> Proteasome Inhibitors.

Michael G Thomas, Kate McGonagle, Paul Rowland

|Apr 27, 2021

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Michael Thomas, Stephen Brand, Manu De Rycker

|Jan 22, 2021

Identification of 6-amino-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidines with <i>in vivo</i> efficacy against visceral leishmaniasis.

Michael G Thomas, Manu De Rycker, Myriam Ajakane

|Jul 15, 2020

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent <i>In Vitro</i> Antileishmanial Activity: Initial SAR and Assessment of <i>In Vivo</i> Activity.

Michael G Thomas, Manu De Rycker, Richard J Wall

|Jan 23, 2020

The Q<sub>i</sub> Site of Cytochrome <i>b</i> is a Promiscuous Drug Target in <i>Trypanosoma cruzi</i> and <i>Leishmania donovani</i>.

Richard J Wall, Sandra Carvalho, Rachel Milne

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Frequent Collaborators

8 joint publications

Manu De Rycker

6 joint publications

Ian H Gilbert

6 joint publications

Kevin D Read

4 joint publications

Susan Wyllie

4 joint publications

Michael Thomas

4 joint publications

Paul G Wyatt

4 joint publications

Maria Marco

3 joint publications

Julio Martin

2 joint publications

Fabio Zuccotto

2 joint publications

Kate McGonagle

Frequent Collaborators

8 joint publications

Manu De Rycker

6 joint publications

Ian H Gilbert

6 joint publications

Kevin D Read

4 joint publications

Susan Wyllie

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