Timothy J Miles

8PUBLICATIONS
35CO-AUTHORS
ChemotherapyCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsBiologically active moleculesBiomolecular modelling and design
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Publications (8)

|Dec 13, 2023
Short-course combination treatment for experimental chronic Chagas disease.

Silvia González, Richard J Wall, John Thomas

|Jul 28, 2023
Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.

Michael G Thomas, Kate McGonagle, Paul Rowland

|Apr 27, 2021
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Michael Thomas, Stephen Brand, Manu De Rycker

|Jan 22, 2021
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis.

Michael G Thomas, Manu De Rycker, Myriam Ajakane

|Jul 15, 2020
Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity.

Michael G Thomas, Manu De Rycker, Richard J Wall

|Jan 23, 2020
The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani.

Richard J Wall, Sandra Carvalho, Rachel Milne

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Frequent Collaborators

8 joint publications

Manu De Rycker

6 joint publications

Ian H Gilbert

6 joint publications

Kevin D Read

4 joint publications

Susan Wyllie