Michael Thomas

7PUBLICATIONS
19CO-AUTHORS
Genomics and transcriptomicsCheminformatics and quantitative structure-activity relationshipsGene and molecular therapy
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Publications (7)

|Feb 04, 2026
Decoding efficacy and resistance space at a drug binding site.

Simone Altmann, Cesar Mendoza-Martinez, Melanie Ridgway

|Jul 02, 2025
Structure-activity relationships of 1,5-dihydro-2<i>H</i>-benzo[<i>b</i>][1,4]diazepine-2,4(3<i>H</i>)-diones as inhibitors of <i>Trypanosoma cruzi</i>.

Michael G Thomas, Joanne Dunne, Peter G Dodd

|Jul 28, 2023
Structure-Guided Design and Synthesis of a Pyridazinone Series of <i>Trypanosoma cruzi</i> Proteasome Inhibitors.

Michael G Thomas, Kate McGonagle, Paul Rowland

|Mar 18, 2022
Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis.

Alasdair Smith, Richard J Wall, Stephen Patterson

|Apr 27, 2021
Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis.

Michael Thomas, Stephen Brand, Manu De Rycker

|Jan 22, 2021
Identification of 6-amino-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidines with <i>in vivo</i> efficacy against visceral leishmaniasis.

Michael G Thomas, Manu De Rycker, Myriam Ajakane

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Frequent Collaborators

6 joint publications

Manu De Rycker

4 joint publications

Maria Marco

4 joint publications

Kevin D Read

4 joint publications

Timothy J Miles