Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Ian R Hardcastle

3PUBLICATIONS
10CO-AUTHORS
Biologically active moleculesBiomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (3)

Sort by Publication Date:
|Nov 11, 2022
Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.

Gemma Davison, Mathew P Martin, Shannon Turberville

|Jul 02, 2021
An Alkynylpyrimidine-Based Covalent Inhibitor That Targets a Unique Cysteine in NF-κB-Inducing Kinase.

Islam Al-Khawaldeh, Mohammed J Al Yasiri, Gregory G Aldred

|Mar 24, 2021
Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.

Gianni Chessari, Ian R Hardcastle, Jong Sook Ahn

Pageof 1

Frequent Collaborators

3 joint publications

Celine Cano

3 joint publications

Duncan C Miller

2 joint publications

Suzannah J Harnor

2 joint publications

Michael J Waring

1 joint publications

Gianni Chessari

1 joint publications

Christopher N Johnson

1 joint publications

Emiliano Tamanini

1 joint publications

Gemma Davison

1 joint publications

James N Sanderson

1 joint publications

Ian Hope

Frequent Collaborators

3 joint publications

Celine Cano

3 joint publications

Duncan C Miller

2 joint publications

Suzannah J Harnor

2 joint publications

Michael J Waring

Top Related Videos

The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS)
07:22

The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS)

Published on : Jan 12, 2024

3.6K
A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on : Nov 02, 2018

9.3K
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
05:17

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on : Feb 09, 2021

1.8K
See more related videos

Top Related Videos

The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS)
07:22

The Development and Application of Biophysical Assays for Evaluating Ternary Complex Formation Induced by Proteolysis Targeting Chimeras (PROTACS)

Published on : Jan 12, 2024

3.6K
A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α
11:27

A Guide to Production, Crystallization, and Structure Determination of Human IKK1/α

Published on : Nov 02, 2018

9.3K
Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay
05:17

Functionalized Spirocyclic Heterocycle Synthesis and Cytotoxicity Assay

Published on : Feb 09, 2021

1.8K
See more related videos