James J Hartman

4PUBLICATIONS
60CO-AUTHORS
Regenerative medicine (incl. stem cells)Energy generation, conversion and storage (excl. chemical and electrical)Gene and molecular therapyBiomolecular modelling and design
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Publications (4)

|Aug 28, 2024
Aficamten is a small-molecule cardiac myosin inhibitor designed to treat hypertrophic cardiomyopathy.

James J Hartman, Darren T Hwee, Julien Robert-Paganin

|Jul 31, 2024
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.

Marloes van den Berg, Zhonghua Shi, Wout J Claassen

|Apr 03, 2024
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease.

Sandra Donkervoort, Martijn van de Locht, Dario Ronchi

|Aug 05, 2017
Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil.

Vicente J Planelles-Herrero, James J Hartman, Julien Robert-Paganin

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