Darren T Hwee

6PUBLICATIONS
68CO-AUTHORS
Energy generation, conversion and storage (excl. chemical and electrical)Gene and molecular therapyNeurology and neuromuscular diseasesCardiology (incl. cardiovascular diseases)Exercise physiology
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Publications (6)

|Jul 31, 2024
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients.

Marloes van den Berg, Zhonghua Shi, Wout J Claassen

|Apr 03, 2024
Pathogenic TNNI1 variants disrupt sarcomere contractility resulting in hypo- and hypercontractile muscle disease.

Sandra Donkervoort, Martijn van de Locht, Dario Ronchi

|Feb 20, 2024
Tirasemtiv enhances submaximal muscle tension in an Acta1:p.Asp286Gly mouse model of nemaline myopathy.

Ricardo A Galli, Tamara C Borsboom, Charlotte Gineste

|Nov 16, 2022
Pharmacokinetics of a single dose of Aficamten (CK-274) on cardiac contractility in a A31P MYBPC3 hypertrophic cardiomyopathy cat model.

Ashley N Sharpe, Maureen S Oldach, Joanna L Kaplan

|Jun 28, 2019
Fast skeletal muscle troponin activator CK-2066260 increases fatigue resistance by reducing the energetic cost of muscle contraction.

Arthur J Cheng, Darren T Hwee, Leo H Kim

|Nov 22, 2016
The Ca2+ sensitizer CK-2066260 increases myofibrillar Ca2+ sensitivity and submaximal force selectively in fast skeletal muscle.

Darren T Hwee, Arthur J Cheng, James J Hartman

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Frequent Collaborators

4 joint publications

Fady I Malik

3 joint publications

Coen A C Ottenheijm

2 joint publications

Arthur J Cheng

2 joint publications

James J Hartman