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Simon Planken

4PUBLICATIONS

18CO-AUTHORS

Molecular targetsCheminformatics and quantitative structure-activity relationships

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Publications (4)

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|May 15, 2023

Efficacy and Imaging-Enabled Pharmacodynamic Profiling of KRAS G12C Inhibitors in Xenograft and Genetically Engineered Mouse Models of Cancer.

Catherine Lee, Ziyue Karen Jiang, Simon Planken

|Dec 28, 2020

Structure-Based Drug Design and Synthesis of PI3Kα-Selective Inhibitor (PF-06843195).

Hengmiao Cheng, Suvi T M Orr, Simon Bailey

|Oct 15, 2020

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19.

Robert L Hoffman, Robert S Kania, Mary A Brothers

|Mar 14, 2017

Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.

Simon Planken, Douglas C Behenna, Sajiv K Nair

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Frequent Collaborators

1 joint publications

Robert L Hoffman

1 joint publications

Jonathan W Lockner

1 joint publications

James A Nieman

1 joint publications

Hengmiao Cheng

1 joint publications

Catherine Lee

1 joint publications

Ziyue Karen Jiang

1 joint publications

Lisa K Manzuk

1 joint publications

Roberto Ortiz

1 joint publications

Michael Hall

1 joint publications

Kavon Noorbehesht

Frequent Collaborators

1 joint publications

Robert L Hoffman

1 joint publications

Jonathan W Lockner

1 joint publications

James A Nieman

1 joint publications

Hengmiao Cheng

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