Maikel Wijtmans

21PUBLICATIONS
52CO-AUTHORS
Biologically active moleculesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsCharacterisation of biological macromoleculesVeterinary anaesthesiology and intensive care
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Publications (21)

|Sep 10, 2026
From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

|Jul 13, 2026
Synthesis of 1,3-Disubstituted 3-Azabicyclo[3.2.0]heptane Libraries for Fragment-Based Drug Discovery.

|Feb 16, 2026
Leveraging fragment-based drug discovery to advance 3D scaffolds into potent ligands: application to the histamine H1 receptor.

Tom Dekker, Oscar P J van Linden, Herman D Lim

|Aug 29, 2025
Design and synthesis of photoswitchable desloratadine ligands for histamine H1 receptor photopharmacology.

Lars C P Binkhorst, Ivana Josimovic, Daan de Vetten

|Jun 26, 2025
A Radiolabeled Photoswitchable G Protein-Coupled Receptor Antagonist Enlightens Ligand Binding Kinetics Associated with Photoswitching.

Lars C P Binkhorst, Ivana Josimovic, Bas De Boer

|Jun 10, 2025
Photo-clenbuterol: Optical Control of β2-Adrenergic Receptor Signaling by Photoswitchable Ligand Efficacy.

Yangzhi Cao, Shuang Shi, Simone A H Does

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Frequent Collaborators

16 joint publications

Rob Leurs

12 joint publications

Henry F Vischer

12 joint publications

Iwan J P de Esch

4 joint publications

Chris de Graaf