Rob Leurs

48PUBLICATIONS
254CO-AUTHORS
Biologically active moleculesBiomolecular modelling and designCheminformatics and quantitative structure-activity relationshipsPharmacogenomicsCharacterisation of biological macromolecules
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Publications (48)

|Sep 10, 2026
From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

|Apr 14, 2026
A Systematic Benchmark Study of Free Energy Methods for Quantifying Light-Responsive Binding Affinities of Photoswitchable Antagonists of Beta-Adrenergic Receptors.

Mohammad Khavani, Amirhossein Bakhtiiari, Laleh Khalvati

|Feb 16, 2026
Leveraging fragment-based drug discovery to advance 3D scaffolds into potent ligands: application to the histamine H1 receptor.

Tom Dekker, Oscar P J van Linden, Herman D Lim

|Dec 29, 2025
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.

Stephen P H Alexander, Anthony P Davenport, Eamonn Kelly

|Jun 26, 2025
A Radiolabeled Photoswitchable G Protein-Coupled Receptor Antagonist Enlightens Ligand Binding Kinetics Associated with Photoswitching.

Lars C P Binkhorst, Ivana Josimovic, Bas De Boer

|Jun 10, 2025
Photo-clenbuterol: Optical Control of β2-Adrenergic Receptor Signaling by Photoswitchable Ligand Efficacy.

Yangzhi Cao, Shuang Shi, Simone A H Does

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Frequent Collaborators

24 joint publications

Henry F Vischer

16 joint publications

Maikel Wijtmans

12 joint publications

Iwan J P de Esch

7 joint publications

Chris De Graaf