Paul Clarke

21PUBLICATIONS
127CO-AUTHORS
Molecular targetsHaematological tumoursWastewater treatment processesMedical devicesWireless communication systems and technologies (incl. microwave and millimetrewave)
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Publications (21)

|Aug 13, 2026
Fragment-Based Discovery of Potent RNA-Competitive Inhibitors of the DEAH-Box RNA Helicase DHX8.

|Mar 16, 2026
Human DEAH-box helicase 8 regulates HSF1-mediated stress response and cancer-associated pre-mRNA splicing in tumour cells.

Jennifer R Tall, Robert Te Poele, Alexandra Vasile

|Feb 17, 2026
R-loop editing by DNA cytosine deaminase APOBEC3B modulates the activity of oestrogen receptor enhancers.

Chi Zhang, Yu-Jing Lu, Bingjie Chen

|Jul 02, 2025
Mediator Kinase Inhibitor Selectivity and Activity in Colorectal Cancer.

Maria J Ortiz-Ruiz, Olajumoke Popoola, Konstantinos Mitsopoulos

|Feb 27, 2025
Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function.

Swee Y Sharp, Marianna Martella, Sabrina D'Agostino

|Feb 14, 2025
Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapy.

Joseph A Newman, Angeline E Gavard, Nergis Imprachim

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Frequent Collaborators

14 joint publications

Paul Workman

4 joint publications

Robert Te-Poele

3 joint publications

Nicola E A Chessum

3 joint publications

Elisa Pasqua