Fabrizio Giordanetto
7PUBLICATIONS
58CO-AUTHORS
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Publications (7)
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|Nov 02, 2023
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.Andreas Varkaris, Ermira Pazolli, Hakan Gunaydin
|Sep 29, 2023
Identification of GDC-1971 (RLY-1971), a SHP2 Inhibitor Designed for the Treatment of Solid Tumors.Alexander M Taylor, Bret R Williams, Fabrizio Giordanetto
|Apr 22, 2023
Discovery and Validation of the Binding Poses of Allosteric Fragment Hits to Protein Tyrosine Phosphatase 1b: From Molecular Dynamics Simulations to X-ray Crystallography.Jack B Greisman, Lindsay Willmore, Christine Y Yeh
|Apr 22, 2022
Discovery by Virtual Screening of an Inhibitor of CDK5-Mediated PPARγ Phosphorylation.Gavin O'Mahony, Jens Petersen, Margareta Ek
|Feb 08, 2022
Molecular Basis of Small-Molecule Binding to α-Synuclein.Paul Robustelli, Alain Ibanez-de-Opakua, Cecily Campbell-Bezat
|Mar 16, 2019
Fragment Hits: What do They Look Like and How do They Bind?Fabrizio Giordanetto, Chentian Jin, Lindsay Willmore
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Frequent Collaborators
5 joint publications
David E Shaw
2 joint publications
Jack B Greisman
2 joint publications
D Randal Kipp
2 joint publications
W Patrick Walters
1 joint publications
Prasanthi Medarametla
1 joint publications
Päivi Tammela
1 joint publications
Simona Collina
1 joint publications
Markus Zweckstetter
1 joint publications
Gavin O'Mahony
1 joint publications
Anders Hogner
