Ignacio Moraga

12PUBLICATIONS
58CO-AUTHORS
Innate immunityMolecular targetsSolid tumoursApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Biologically active molecules
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Publications (12)

|Mar 07, 2024
Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency.

Scott Gardner, Yibo Jin, Paul K Fyfe

|Dec 02, 2022
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein.

Silvia Gaggero, Jonathan Martinez-Fabregas, Adeline Cozzani

|Aug 08, 2022
Engineered IL13 variants direct specificity of IL13Rα2-targeted CAR T cell therapy.

Lawrence A Stern, Sharareh Gholamin, Ignacio Moraga

|Aug 03, 2022
Structural insights into the assembly and activation of the IL-27 signaling complex.

Yibo Jin, Paul K Fyfe, Scott Gardner

|Mar 05, 2022
Molecular and cellular factors determining the functional pleiotropy of cytokines.

Alison McFarlane, Elizabeth Pohler, Ignacio Moraga

|Apr 19, 2021
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses.

Stephan Wilmes, Polly-Anne Jeffrey, Jonathan Martinez-Fabregas

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Frequent Collaborators

6 joint publications

Jacob Piehler

6 joint publications

Stephan Wilmes

5 joint publications

Paul K Fyfe

3 joint publications

K Christopher Garcia