David J Hirst

6PUBLICATIONS
26CO-AUTHORS
Innate immunityBiomolecular modelling and designBiologically active moleculesOrganometallic chemistry
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Publications (6)

|Jun 22, 2026
Discovery of an Orally Available Potent ER Aminopeptidase 1 (ERAP1) Inhibitor That Enhances Antitumor Responses and Limits Inflammatory Autoimmunity In Vivo.

|Apr 13, 2026
Automated Molecular Design in BRADSHAW, Applied to the Optimization of ERAP1 Inhibitors.

Robert P Law, Ian D Wall, Richard Lonsdale

|Sep 21, 2020
A Turing Test for Molecular Generators.

Jacob T Bush, Peter Pogany, Stephen D Pickett

|Jan 07, 2020
Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening.

Christopher R Wellaway, Dominique Amans, Paul Bamborough

|Jul 07, 2018
Atom Efficient Synthesis of Selectively Difluorinated Carbocycles through a Gold(I)-Catalyzed Cyclization.

Adam W McCarter, Magdalena Sommer, Jonathan M Percy

|Apr 17, 2018
Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.

Robert P Law, Stephen J Atkinson, Paul Bamborough

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Frequent Collaborators

2 joint publications

Peter Pogany

2 joint publications

Stephen D Pickett

2 joint publications

Christopher P Tinworth

2 joint publications

Efstratios Stratikos