Yiyou Huang

6PUBLICATIONS
11CO-AUTHORS
Biologically active moleculesMedical bacteriologyToxicology (incl. clinical toxicology)Pharmaceutical delivery technologiesCheminformatics and quantitative structure-activity relationships
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Publications (6)

|May 27, 2026
Design, Synthesis, and Evaluation of Braylin Derivatives as Novel PDE4 Inhibitors with Anti-Inflammatory Effects.

|Jan 23, 2026
Discovery of Novel MDH2 Inhibitor 28i by Secondary Development of Glibenclamide with Potent Antiaging Activities.

Lingyu Wu, Ru Zeng, Shuman Huang

|Nov 21, 2025
Structure-Based Optimization of Imidazopyridine Derivatives as Selective and Orally Bioavailable Phosphodiesterase 10A Inhibitors with Reduced Blood-Brain Barrier Penetration for the Treatment of Idiopathic Pulmonary Fibrosis.

Fengcai Zhang, Han Yuan, Siqi Yao

|Nov 18, 2025
Artificial Intelligence-Driven Discovery of Pyrazolo[1,5-a]pyrimidine Derivatives as Novel Phosphodiesterase 4 Inhibitors for Treating Idiopathic Pulmonary Fibrosis.

Zheng Li, Wanting Huan, Xingfu Liu

|Feb 28, 2020
Discovery and Optimization of Chromone Derivatives as Novel Selective Phosphodiesterase 10 Inhibitors.

Yan-Fa Yu, Chen Zhang, Yi-You Huang

|Mar 20, 2019
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.

Yi-You Huang, Yan-Fa Yu, Chen Zhang

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Frequent Collaborators

3 joint publications

Hai-Bin Luo

2 joint publications

Deyan Wu

2 joint publications

Yinuo Wu

2 joint publications

Lei Guo