Shengzhe Shang

3PUBLICATIONS
8CO-AUTHORS
HaematologyEpigenetics (incl. genome methylation and epigenomics)Gene and molecular therapy
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (3)

|Aug 01, 2026
Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells.

|Aug 08, 2023
Analysis of the complex between MBD2 and the histone deacetylase core of NuRD reveals key interactions critical for gene silencing.

Gage O Leighton, Shengzhe Shang, Sean Hageman

|Jun 12, 2023
MBD2a-NuRD binds to the methylated γ-globin gene promoter and uniquely forms a complex required for silencing of HbF expression.

Shengzhe Shang, Xia Li, Alexander Azzo

Pageof 1

Frequent Collaborators

3 joint publications

David C Williams

3 joint publications

Gordon D Ginder

2 joint publications

Mikhail Dozmorov

1 joint publications

Charles Lyons