David C Williams

11PUBLICATIONS
42CO-AUTHORS
Characterisation of biological macromoleculesEpigenetics (incl. genome methylation and epigenomics)HaematologyAgricultural molecular engineering of nucleic acids and proteinsGene and molecular therapy
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (11)

|Oct 29, 2026
Macrocycle Screening against the C-Terminal Region of CHD4 Uncovers Its Role as an Interaction Hub in the Formation of the Nucleosome Remodeling and Deacetylase Complex.

|Oct 19, 2026
Exploring the bistable equilibrium of methylated CpG DNA recognition by the MBD2 protein.

|Aug 01, 2026
Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells.

|Jun 12, 2026
Macrocycle screening against the C-terminal region of CHD4 uncovers its role as an interaction hub in the formation of the nucleosome remodeling and deacetylase complex.

|Jan 26, 2026
DNA methylation matters: methylation of the γ-globin (HBG) gene promoters is required for postnatal silencing of HbF.

Gordon D Ginder, Shengzhe Shang, David C Williams

|Jul 25, 2025
Methyl-CpG-binding domain as a protein interaction partner in promoter regulation and neurodevelopment through evolutionary expanded entanglement.

Stephanie M Bilinovich, Surya B Chhetri, Jackson T Mitchell

Pageof 2

Frequent Collaborators

3 joint publications

Gordon D Ginder

3 joint publications

Shengzhe Shang

2 joint publications

Gage O Leighton

2 joint publications

Mikhail Dozmorov