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Kathleen M Ruppel

7PUBLICATIONS
16CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Medical devices
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Journal

Publications (7)

Sort by Publication Date:
|Oct 01, 2025
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically.

Neha Nandwani, Debanjan Bhowmik, Camille Glaser

|Aug 27, 2024
Reassessing the unifying hypothesis for hypercontractility caused by myosin mutations in hypertrophic cardiomyopathy.

James A Spudich, Neha Nandwani, Julien Robert-Paganin

|Mar 11, 2024
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically.

Neha Nandwani, Debanjan Bhowmik, Matthew C Childers

|May 31, 2023
Cryo-EM structure of the folded-back state of human β-cardiac myosin.

Alessandro Grinzato, Daniel Auguin, Carlos Kikuti

|Jun 29, 2022
Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function.

Makenna M Morck, Debanjan Bhowmik, Divya Pathak

|Apr 15, 2020
The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin.

Saswata S Sarkar, Darshan V Trivedi, Makenna M Morck

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Frequent Collaborators

6 joint publications

James A Spudich

4 joint publications

Neha Nandwani

3 joint publications

Anne Houdusse

2 joint publications

Saswata S Sarkar

2 joint publications

Makenna M Morck

2 joint publications

Debanjan Bhowmik

2 joint publications

Julien Robert-Paganin

1 joint publications

Arjun S Adhikari

1 joint publications

Aminah Dawood

1 joint publications

Darshan V Trivedi

Frequent Collaborators

6 joint publications

James A Spudich

4 joint publications

Neha Nandwani

3 joint publications

Anne Houdusse

2 joint publications

Saswata S Sarkar

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