Kathleen M Ruppel
7PUBLICATIONS
16CO-AUTHORS
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Publications (7)
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|Oct 01, 2025
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically.Neha Nandwani, Debanjan Bhowmik, Camille Glaser
|Mar 11, 2024
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human beta-cardiac myosin allosterically.Neha Nandwani, Debanjan Bhowmik, Matthew C Childers
|May 31, 2023
Cryo-EM structure of the folded-back state of human β-cardiac myosin.Alessandro Grinzato, Daniel Auguin, Carlos Kikuti
|Jun 29, 2022
Hypertrophic cardiomyopathy mutations in the pliant and light chain-binding regions of the lever arm of human β-cardiac myosin have divergent effects on myosin function.Makenna M Morck, Debanjan Bhowmik, Divya Pathak
|Apr 15, 2020
The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin.Saswata S Sarkar, Darshan V Trivedi, Makenna M Morck
|Jun 20, 2019
β-Cardiac myosin hypertrophic cardiomyopathy mutations release sequestered heads and increase enzymatic activity.Arjun S Adhikari, Darshan V Trivedi, Saswata S Sarkar
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Frequent Collaborators
6 joint publications
James A Spudich
4 joint publications
Neha Nandwani
3 joint publications
Anne Houdusse
2 joint publications
Saswata S Sarkar
2 joint publications
Makenna M Morck
2 joint publications
Debanjan Bhowmik
2 joint publications
Julien Robert-Paganin
1 joint publications
Arjun S Adhikari
1 joint publications
Aminah Dawood
1 joint publications
Darshan V Trivedi
