James Spudich

20PUBLICATIONS
66CO-AUTHORS
Molecular medicineGene and molecular therapyCardiology (incl. cardiovascular diseases)Cell physiologyCellular immunology
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Publications (20)

|Jul 24, 2026
Antimalarial cytoskeletal targeting with broad apicomplexan activity.

|Jul 07, 2026
Mavacamten shows broad benefit in human and mouse models of MYBPC3-related hypertrophic cardiomyopathy.

|Jun 04, 2026
Dynamics of the β-cardiac myosin auto-inhibited state explain cardiomyopathy pathogenesis.

|May 05, 2026
The hypertrophic cardiomyopathy myosin variant G256E prolongs cardiac muscle relaxation via altered nucleotide handling.

|Nov 24, 2025
The G256E HCM mutation prolongs cardiac muscle relaxation via altered nucleotide handling.

Michael Regnier, Kerry Kao, Matthew Childers

|Oct 01, 2025
Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically.

Neha Nandwani, Debanjan Bhowmik, Camille Glaser

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Frequent Collaborators

6 joint publications

Kathleen M Ruppel

5 joint publications

Anne Houdusse

5 joint publications

Neha Nandwani

3 joint publications

Julien Robert-Paganin