Michael J Holliday

6PUBLICATIONS
65CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsMolecular targetsAutonomic nervous systemCardiology (incl. cardiovascular diseases)
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Publications (6)

|Aug 12, 2026
Cryptic small-molecule binding sites in the ARID1B DNA-binding domain.

|Apr 09, 2026
Nanoscale Direct-to-Biology Optimization of Cdk2 Inhibitors.

James L Douthwaite, Damian J Houde, Eneida Pardo

|Nov 02, 2023
Discovery and Clinical Proof-of-Concept of RLY-2608, a First-in-Class Mutant-Selective Allosteric PI3Kα Inhibitor That Decouples Antitumor Activity from Hyperinsulinemia.

Andreas Varkaris, Ermira Pazolli, Hakan Gunaydin

|Jul 28, 2021
Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif.

Mark Ultsch, Michael J Holliday, Stefan Gerhardy

|Jul 13, 2019
Structures of autoinhibited and polymerized forms of CARD9 reveal mechanisms of CARD9 and CARD11 activation.

Michael J Holliday, Axel Witt, Alejandro Rodríguez Gama

|Sep 13, 2018
Picomolar zinc binding modulates formation of Bcl10-nucleating assemblies of the caspase recruitment domain (CARD) of CARD9.

Michael J Holliday, Ryan Ferrao, Gladys de Leon Boenig

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Frequent Collaborators

3 joint publications

Wayne J Fairbrother

2 joint publications

Alessandro A Boezio

2 joint publications

Alexis Rohou

2 joint publications

Kelley Shortsleeves