Guillaume M Hautbergue

15PUBLICATIONS
57CO-AUTHORS
Neurology and neuromuscular diseasesCancer therapy (excl. chemotherapy and radiation therapy)Environmentally sustainable engineeringCell and nuclear divisionPredictive and prognostic markers
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Publications (15)

|Feb 27, 2026
Antisense Dipeptide Repeat Proteins Drive Widescale Purine Metabolism Aberration in C9orf72 Amyotrophic Lateral Sclerosis via ADA.

Benjamin Hall, Lydia Castelli, Adrian Higginbottom

|Dec 05, 2024
RuvBL1/2 reduce toxic dipeptide repeat protein burden in multiple models of C9orf72-ALS/FTD.

Christopher P Webster, Bradley Hall, Olivia M Crossley

|Sep 07, 2023
The master energy homeostasis regulator PGC-1α exhibits an mRNA nuclear export function.

Simeon R Mihaylov, Lydia M Castelli, Ya-Hui Lin

|Mar 01, 2023
A cell-penetrant peptide blocking C9ORF72-repeat RNA nuclear export reduces the neurotoxic effects of dipeptide repeat proteins.

Lydia M Castelli, Ya-Hui Lin, Alvaro Sanchez-Martinez

|Oct 14, 2022
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.

Tobias Moll, Valerie Odon, Calum Harvey

|May 14, 2022
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons.

Paolo M Marchi, Lara Marrone, Laurent Brasseur

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