Thomas Knoepfel

8PUBLICATIONS
20CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)AutoimmunityInnate immunityCheminformatics and quantitative structure-activity relationshipsMolecular targets
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Publications (8)

|Dec 08, 2025
Harnessing Glutamine-117 Plasticity toward Structure-Based Identification of Triazole IL-17 Inhibitors.

Matthias R Bauer, Juraj Velcicky, Alban Goetz

|Dec 23, 2024
Thiazole-Based IL-17 Inhibitors Discovered by Scaffold Morphing.

Juraj Velcicky, Estelle Ngo, Matthias R Bauer

|Sep 14, 2024
Discovery and In Vivo Exploration of 1,3,4-Oxadiazole and α-Fluoroacrylate Containing IL-17 Inhibitors.

Juraj Velcicky, Matthias R Bauer, Achim Schlapbach

|Aug 16, 2023
Discovery of the TLR7/8 Antagonist MHV370 for Treatment of Systemic Autoimmune Diseases.

Phil Alper, Claudia Betschart, Cédric André

|Apr 22, 2022
Structure-Based Optimization of a Fragment-like TLR8 Binding Screening Hit to an In Vivo Efficacious TLR7/8 Antagonist.

Claudia Betschart, Michael Faller, Florence Zink

|Sep 15, 2020
Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4.

Robin A Fairhurst, Thomas Knoepfel, Nicole Buschmann

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