Shiho Yamamoto

6PUBLICATIONS
19CO-AUTHORS
Nanoelectromechanical systemsBiologically active moleculesBiomolecular modelling and designPredictive and prognostic markersCheminformatics and quantitative structure-activity relationships
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Publications (6)

|Apr 15, 2026
Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide N‑Methyltransferase.

Shuhei Yoshida, Noriyasu Kondo, Shota Uehara

|Jul 05, 2025
Discovery of the Clinical Candidate S-892216: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19.

Yuto Unoh, Keiichiro Hirai, Shota Uehara

|Jul 29, 2022
Peptide-to-Small Molecule: A Pharmacophore-Guided Small Molecule Lead Generation Strategy from High-Affinity Macrocyclic Peptides.

Shuhei Yoshida, Shota Uehara, Noriyasu Kondo

|Mar 30, 2022
Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19.

Yuto Unoh, Shota Uehara, Kenji Nakahara

|Sep 23, 2021
Discovery of Extremely Selective Fused Pyridine-Derived β-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions.

Tatsuhiko Ueno, Eriko Matsuoka, Naoya Asada

|Jul 16, 2021
Macrocyclic Peptides as a Novel Class of NNMT Inhibitors: A SAR Study Aimed at Inhibitory Activity in the Cell.

Kyohei Hayashi, Shota Uehara, Shiho Yamamoto

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Frequent Collaborators

5 joint publications

Shota Uehara

4 joint publications

Yuki Tachibana

2 joint publications

Shuhei Yoshida

1 joint publications

Kyohei Hayashi