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Birgit Wilding

6PUBLICATIONS

42CO-AUTHORS

Proteins and peptidesMolecular targetsFree radical chemistryBiologically active molecules

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Publications (6)

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|Apr 23, 2025

Discovery of Carbodiimide Warheads to Selectively and Covalently Target Aspartic Acid in KRAS<sup>G12D</sup>.

Ludovica S Sirocchi, Maximilian Scharnweber, Sarah Oberndorfer

|Sep 09, 2024

Zongertinib (BI 1810631), an Irreversible HER2 TKI, Spares EGFR Signaling and Improves Therapeutic Response in Preclinical Models and Patients with HER2-Driven Cancers.

Birgit Wilding, Lydia Woelflingseder, Anke Baum

|Jul 26, 2022

Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.

Birgit Wilding, Dirk Scharn, Dietrich Böse

|Feb 07, 2022

Chemoenzymatic one-pot reaction from carboxylic acid to nitrile <i>via</i> oxime.

Melissa Horvat, Victoria Weilch, Robert Rädisch

|Dec 15, 2017

Demonstrating In-Cell Target Engagement Using a Pirin Protein Degradation Probe (CCT367766).

Nicola E A Chessum, Swee Y Sharp, John J Caldwell

|Dec 23, 2016

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen.

Matthew D Cheeseman, Nicola E A Chessum, Carl S Rye

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Frequent Collaborators

2 joint publications

Keith Jones

2 joint publications

Ralph A Neumüller

2 joint publications

Flavio Solca

2 joint publications

Daniel Gerlach

1 joint publications

Nicola E A Chessum

1 joint publications

A Elisa Pasqua

1 joint publications

Krzysztof M Zak

1 joint publications

Bugra Ozer

1 joint publications

Mark Stubbs

1 joint publications

Paul A Clarke

Frequent Collaborators

2 joint publications

Keith Jones

2 joint publications

Ralph A Neumüller

2 joint publications

Flavio Solca

2 joint publications

Daniel Gerlach

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