Yi Yu

9PUBLICATIONS
152CO-AUTHORS
Molecular targetsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (9)

|Sep 02, 2026
Suppressing phosphatidylserine externalization overcomes cancer immune evasion and enhances immunotherapy.

|Jun 10, 2026
TNG917 is a Potent and Selective Inhibitor of Histone Lysine Methyltransferases EHMT1/2 that Enhances Antitumor Immunity and Immunotherapy Efficacy.

|Apr 19, 2026
TNG961 Is a Selective Oral HBS1L Molecular Glue Degrader for the Treatment of FOCAD-Deleted Cancers.

|Aug 29, 2025
TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.

Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang

|May 06, 2025
CRISPR Screens Identify POLB as a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-Mutated Tumors.

Katherine Lazarides, Justin L Engel, Michele Meseonznik

|Jan 31, 2025
Characterization of TNG348: A Selective, Allosteric USP1 Inhibitor That Synergizes with PARP Inhibitors in Tumors with Homologous Recombination Deficiency.

Antoine Simoneau, Charlotte B Pratt, Hsin-Jung Wu

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Frequent Collaborators

7 joint publications

Jannik N Andersen

6 joint publications

Samuel R Meier

6 joint publications

Douglas A Whittington

5 joint publications

John P Maxwell