Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Samuel R Meier

6PUBLICATIONS
101CO-AUTHORS
Molecular targets
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

Sort by Publication Date:
|Apr 19, 2026
TNG961 is a selective oral HBS1L molecular glue degrader for the treatment of FOCAD-deleted cancers.

|Aug 29, 2025
TNG260 Is a Small-Molecule CoREST Inhibitor That Sensitizes STK11-Mutant Tumors to Anti-PD-1 Immunotherapy.

Leanne G Ahronian, Soumyadip Sahu, Minjie Zhang

|May 06, 2025
CRISPR Screens Identify POLB as a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-Mutated Tumors.

Katherine Lazarides, Justin L Engel, Michele Meseonznik

|Jan 31, 2025
Characterization of TNG348: A Selective, Allosteric USP1 Inhibitor That Synergizes with PARP Inhibitors in Tumors with Homologous Recombination Deficiency.

Antoine Simoneau, Charlotte B Pratt, Hsin-Jung Wu

|Oct 13, 2022
Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer.

Antoine Simoneau, Justin L Engel, Madhavi Bandi

|Sep 07, 2022
VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient Glioblastoma.

Julie A Shields, Samuel R Meier, Madhavi Bandi

Pageof 1

Frequent Collaborators

6 joint publications

Jannik N Andersen

5 joint publications

Douglas A Whittington

5 joint publications

Alan Huang

5 joint publications

Yi Yu

5 joint publications

Binzhang Shen

4 joint publications

Madhavi Bandi

4 joint publications

John P Maxwell

4 joint publications

Minjie Zhang

3 joint publications

Yingnan Chen

3 joint publications

Justin L Engel

Frequent Collaborators

6 joint publications

Jannik N Andersen

5 joint publications

Douglas A Whittington

5 joint publications

Alan Huang

5 joint publications

Yi Yu

Top Related Videos

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on : Nov 09, 2020

11.7K
Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on : Jul 25, 2020

7.4K
Pooled CRISPR-Based Genetic Screens in Mammalian Cells
00:09

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Published on : Sep 04, 2019

21.5K
See more related videos

Top Related Videos

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
05:33

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines

Published on : Nov 09, 2020

11.7K
Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on : Jul 25, 2020

7.4K
Pooled CRISPR-Based Genetic Screens in Mammalian Cells
00:09

Pooled CRISPR-Based Genetic Screens in Mammalian Cells

Published on : Sep 04, 2019

21.5K
See more related videos