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Tod Harper

6PUBLICATIONS

7CO-AUTHORS

Gene and molecular therapyMolecular targets

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Publications (6)

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|Jan 21, 2026

An Industry Perspective on Key Considerations for the ICH S13 Guidance: Nonclinical Safety Evaluations of Oligonucleotide-Based Therapeutics.

Jennifer D Sisler, Patrik Andersson, Alan Brown

|Sep 03, 2025

Use of a Transgenic Human PNPLA3<sup>I148M</sup> Knock-in Mouse for Translational Safety Evaluations of siRNA Therapeutics.

Ben Brooks, Artem Shkumatov, Jackson Kalanzi

|Feb 06, 2025

Assessing Hybridization-Dependent Off-Target Risk for Therapeutic Oligonucleotides: Updated Industry Recommendations.

Patrik Andersson, Sebastien A Burel, Heather Estrella

|Jan 23, 2025

Opportunities for More Tailored Approaches to Genotoxicity Testing and Carcinogenicity Strategy for Oligonucleotide Therapeutics: Outcome of an Industry Survey.

Joel D Parry, Tod A Harper, Patrik Andersson

|Feb 16, 2024

Scientific Review of the Proarrhythmic Risks of Oligonucleotide Therapeutics: Are Dedicated ICH S7B/E14 Studies Needed for Low-Risk Modalities?

Yusheng Qu, Kim A Henderson, Tod A Harper

|May 18, 2022

Characterization of an Anti-CD70 Half-Life Extended Bispecific T-Cell Engager (HLE-BiTE) and Associated On-Target Toxicity in Cynomolgus Monkeys.

Tod Harper, Amy Sharma, Sarav Kaliyaperumal

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Frequent Collaborators

3 joint publications

Patrik Andersson

1 joint publications

Yusheng Qu

1 joint publications

Hugo M Vargas

1 joint publications

Ingrid C Rulifson

1 joint publications

Jennifer D Sisler

1 joint publications

Alan Brown

1 joint publications

Michaël Maes

Frequent Collaborators

3 joint publications

Patrik Andersson

1 joint publications

Yusheng Qu

1 joint publications

Hugo M Vargas

1 joint publications

Ingrid C Rulifson

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