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James Cregg

4PUBLICATIONS

45CO-AUTHORS

Molecular targets

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Publications (4)

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|Jun 22, 2026

Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers.

|Mar 08, 2025

Discovery of Daraxonrasib (RMC-6236), a Potent and Orally Bioavailable RAS(ON) Multi-selective, Noncovalent Tri-complex Inhibitor for the Treatment of Patients with Multiple RAS-Addicted Cancers.

James Cregg, Anne V Edwards, Stephanie Chang

|Feb 24, 2025

Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers.

James Cregg, Kristof Pota, Aidan C A Tomlinson

|Apr 09, 2024

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.

Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato

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Frequent Collaborators

4 joint publications

Elena S Koltun

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Jingjing Jiang

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Abby Marquez

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Benjamin J Maldonato

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Matthew Holderfield

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Adrian L Gill

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Kyle J Seamon

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John E Knox

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Zhican Wang

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Xing Wei

Frequent Collaborators

4 joint publications

Elena S Koltun

2 joint publications

Jingjing Jiang

2 joint publications

Abby Marquez

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Benjamin J Maldonato