Matthew Holderfield

7PUBLICATIONS
148CO-AUTHORS
Molecular targets
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Publications (7)

|Jun 22, 2026
Targeting KRAS codon 13 mutations using direct combination approaches in non-small cell lung cancer.

|Jun 22, 2026
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers.

|May 22, 2026
Genetic Drivers of Sensitivity or Resistance to RAS(ON) Multi-Selective Inhibitors in NRAS-Mutated Melanoma.

|Feb 11, 2026
Abrogation of Oncogenic RAS Signaling by a RAS(ON) Inhibitor Doublet Primes Immune-Refractory KRASG12C-Mutant NSCLC for Immune Checkpoint Blockade.

Xing Wei, Cristina Blaj, M Ali Al-Radhawi

|Jul 24, 2025
A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

Caroline Weller, G Leslie Burnett, Lingyan Jiang

|Apr 09, 2024
Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.

Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato

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Frequent Collaborators

6 joint publications

Mallika Singh

5 joint publications

Jacqueline A M Smith

5 joint publications

Jingjing Jiang

4 joint publications

Zhican Wang