Kyle Seamon

5PUBLICATIONS

106CO-AUTHORS

Molecular targetsBiomolecular modelling and design

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Publications (5)

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|Jun 22, 2026

Targeting KRAS codon 13 mutations using direct combination approaches in non-small cell lung cancer.

|Jun 22, 2026

Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers.

|Jul 24, 2025

A neomorphic protein interface catalyzes covalent inhibition of RAS<sup>G12D</sup> aspartic acid in tumors.

Caroline Weller, G Leslie Burnett, Lingyan Jiang

|Apr 09, 2024

Translational and Therapeutic Evaluation of RAS-GTP Inhibition by RMC-6236 in RAS-Driven Cancers.

Jingjing Jiang, Lingyan Jiang, Benjamin J Maldonato

|Aug 17, 2023

Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS.

Christopher J Schulze, Kyle J Seamon, Yulei Zhao

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Frequent Collaborators

Jacqueline A M Smith

Matthew Holderfield

Elena S Koltun

Mallika Singh

Abby Marquez

Jingjing Jiang

David Wildes

Zhican Wang

Aidan Tomlinson

Adrian L Gill

Frequent Collaborators

Jacqueline A M Smith

Matthew Holderfield

Elena S Koltun

Mallika Singh