Jacqueline A M Smith

15PUBLICATIONS
185CO-AUTHORS
Molecular targetsBiomolecular modelling and design
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Publications (15)

|Aug 11, 2026
Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer.

|Jun 22, 2026
Targeting KRAS codon 13 mutations using direct combination approaches in non-small cell lung cancer.

|Jun 22, 2026
Selective Inhibition of KRASG13C Reveals an Increased Dependence on Wild-Type RAS Isoforms in Codon 13 RAS-Mutant Cancers.

|Feb 11, 2026
Abrogation of Oncogenic RAS Signaling by a RAS(ON) Inhibitor Doublet Primes Immune-Refractory KRASG12C-Mutant NSCLC for Immune Checkpoint Blockade.

Xing Wei, Cristina Blaj, M Ali Al-Radhawi

|Jul 24, 2025
A neomorphic protein interface catalyzes covalent inhibition of RASG12D aspartic acid in tumors.

Caroline Weller, G Leslie Burnett, Lingyan Jiang

|Nov 12, 2024
Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.

Urszula N Wasko, Jingjing Jiang, Tanner C Dalton

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Frequent Collaborators

8 joint publications

Mallika Singh

6 joint publications

Jingjing Jiang

6 joint publications

David Wildes

6 joint publications

Andrew J Aguirre