Willem A L van Otterlo

13PUBLICATIONS
37CO-AUTHORS
Biomolecular modelling and designTheory and design of materialsBiologically active moleculesOrganometallic chemistryMolecular targets
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Journal

Publications (13)

|Jun 03, 2025
Metabolic Activation versus Masked Prodrugs: Bisubstrate Mimic Inhibitors of CoaBC's PPCS Activity in Mycobacterium tuberculosis and Staphylococcus aureus.

Timothy J Kotzé, Konrad J Mostert, Riyad Domingo

|Oct 21, 2024
The role of silicon in drug discovery: a review.

Jenny-Lee Panayides, Darren Lyall Riley, Felix Hasenmaile

|Jun 19, 2024
Sphaeropsidin A C15-C16 Cross-Metathesis Analogues with Potent Anticancer Activity.

Sachin B Wagh, Dino Berthold, Iram Majeed

|Jun 12, 2024
Improved Rigidin-Inspired Antiproliferative Agents with Modifications on the 7-Deazahypoxanthine C7/C8 Ring Systems.

Aletta E van der Westhuyzen, Naghmana Ashraf, Daleen Conradie

|Jul 29, 2023
Unprecedented Direct Asymmetric Total Syntheses of 5,8'-Naphthylisoquinoline Alkaloids from their Fully Substituted Precursors Employing a Novel Nickel/N,N-ligand-Catalyzed Atroposelective Cross-Coupling Reaction.

Dino Berthold, Willem A L van Otterlo

|Nov 24, 2022
A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.

Akash Sabarwal, Jaco C van Rooyen, Jeremy Caburet

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Frequent Collaborators

3 joint publications

Erick Strauss

3 joint publications

Alexander Kornienko

2 joint publications

Charles B de Koning

1 joint publications

Erick T Tjhin