Makiko Shimizu

24PUBLICATIONS
25CO-AUTHORS
Process control and simulationCancer diagnosisToxicology (incl. clinical toxicology)PharmacogenomicsMetabolic medicine
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Publications (24)

|Jul 21, 2025
In Vitro Assessment of Drug-Induced Liver Injury Using Three-Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver.

Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto

|Sep 17, 2024
Urinary bladder carcinogenic potential of 4,4'-methylenebis(2-chloroaniline) in humanized-liver mice.

Shugo Suzuki, Min Gi, Takuma Kobayashi

|Nov 08, 2023
Empirical scaling factor for predicting human pharmacokinetic profiles of disproportionate metabolites using the Css-MRTpo method and chimeric mice with humanised livers.

Hidetaka Kamimura, Shotaro Uehara, Nao Yoneda

|Oct 06, 2023
Cytochrome P450 1A2 and 2C enzymes autoinduced by omeprazole in dog hepatocytes and human HepaRG and HepaSH cells are involved in omeprazole 5-hydroxylation and sulfoxidation.

Yasuhiro Uno, Shotaro Uehara, Genki Ushirozako

|Jan 09, 2023
The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers.

Shotaro Uehara, Yuichiro Higuchi, Nao Yoneda

|Sep 23, 2022
Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets.

Shogo Matsumoto, Shotaro Uehara, Hidetaka Kamimura

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Frequent Collaborators

15 joint publications

Shotaro Uehara

14 joint publications

Hiroshi Yamazaki

3 joint publications

Hidetaka Kamimura

1 joint publications

Raghubendra Singh Dagur