Shahram Misaghi

13PUBLICATIONS
10CO-AUTHORS
Epigenetics (incl. genome methylation and epigenomics)Bioprocessing, bioproduction and bioproductsWastewater treatment processesMedical molecular engineering of nucleic acids and proteinsFermentation
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Publications (13)

|Oct 30, 2024
Chromatin Accessibility Plays an Important Epigenetic Role on Antibody Expression From CMV Promoter and DNA Elements Flanking the CHO TI Host Landing-Pad.

Kavya Ganapathy, Andrew McKay, Steffen Durinck

|May 10, 2023
Activation of the PERK branch of the unfolded protein response during production reduces specific productivity in CHO cells via downregulation of PDGFRa and IRE1a signaling.

Brian M Castellano, Danming Tang, Scot Marsters

|Mar 06, 2023
Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth.

Cynthia Lam, Joseph Carver, Domingos Ng

|Dec 20, 2022
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study.

Danming Tang, Jane Gunson, Eric Tran

|Dec 24, 2021
Bax and Bak knockout apoptosis-resistant Chinese hamster ovary cell lines significantly improve culture viability and titer in intensified fed-batch culture process.

Danming Tang, Cynthia Lam, Niels Bauer

|Jul 21, 2021
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.

Danming Tang, Wendy Sandoval, Peter Liu

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Frequent Collaborators

6 joint publications

Danming Tang

4 joint publications

David Shaw

3 joint publications

Amy Shen

1 joint publications

Cynthia Lam