Danming Tang
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8CO-AUTHORS
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Publications (8)
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|May 10, 2023
Activation of the PERK branch of the unfolded protein response during production reduces specific productivity in CHO cells via downregulation of PDGFRa and IRE1a signaling.Brian M Castellano, Danming Tang, Scot Marsters
|Mar 06, 2023
Combining regulated and constitutive protein expression significantly boosts protein expression by increasing productivity without affecting CHO cell growth.Cynthia Lam, Joseph Carver, Domingos Ng
|Dec 20, 2022
Expressing antigen binding fragments with high titers in a targeted integration CHO host by optimizing expression vector gene copy numbers and position: A case study.Danming Tang, Jane Gunson, Eric Tran
|Dec 24, 2021
Bax and Bak knockout apoptosis-resistant Chinese hamster ovary cell lines significantly improve culture viability and titer in intensified fed-batch culture process.Danming Tang, Cynthia Lam, Niels Bauer
|Sep 19, 2021
A ribonucleoprotein-based decaplex CRISPR/Cas9 knockout strategy for CHO host engineering.Joseph Carver, Marie Kern, Peggy Ko
|Jul 21, 2021
Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.Danming Tang, Wendy Sandoval, Peter Liu
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