Katherine A Davies

6PUBLICATIONS
26CO-AUTHORS
Molecular targetsMedical infection agents (incl. prions)
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (6)

|Oct 26, 2023
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization.

Yanxiang Meng, Sarah E Garnish, Katherine A Davies

|Apr 28, 2023
The VEGFR/PDGFR tyrosine kinase inhibitor, ABT-869, blocks necroptosis by targeting RIPK1 kinase.

Catia L Pierotti, Annette V Jacobsen, Christoph Grohmann

|Mar 10, 2022
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL.

Ashish Sethi, Christopher R Horne, Cheree Fitzgibbon

|Nov 23, 2021
Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis.

Yanxiang Meng, Katherine A Davies, Cheree Fitzgibbon

|Jun 21, 2020
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.

Katherine A Davies, Cheree Fitzgibbon, Samuel N Young

|Jun 21, 2020
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis.

Andre L Samson, Ying Zhang, Niall D Geoghegan

Pageof 1