Christopher R Horne

16PUBLICATIONS
64CO-AUTHORS
Medical infection agents (incl. prions)Nanoscale characterisationMolecular targetsEpidemiological modellingGenome structure and regulation
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Publications (16)

|Feb 03, 2026
The kinase domain of RIPK3 tunes its scaffolding functions.

Shene Chiou, Christopher R Horne, Komal M Patel

|Dec 22, 2025
Mechanism of NanR transcriptional activation of sialic acid metabolism in Streptococcus pneumoniae.

David M Wood, Ashleigh S Johns, Zachary D Tillett

|Aug 13, 2024
Inhibitors identify an auxiliary role for mTOR signalling in necroptosis execution downstream of MLKL activation.

Sarah E Garnish, Christopher R Horne, Yanxiang Meng

|Oct 26, 2023
Phosphorylation-dependent pseudokinase domain dimerization drives full-length MLKL oligomerization.

Yanxiang Meng, Sarah E Garnish, Katherine A Davies

|Sep 28, 2023
A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation.

Sarah E Garnish, Katherine R Martin, Maria Kauppi

|Jun 23, 2022
Human RIPK3 C-lobe phosphorylation is essential for necroptotic signaling.

Yanxiang Meng, Christopher R Horne, Andre L Samson

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