Liping Pettus

6PUBLICATIONS
52CO-AUTHORS
Molecular targetsMedical infection agents (incl. prions)Cheminformatics and quantitative structure-activity relationshipsBiomaterials
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Publications (6)

|Jul 14, 2026
Expanding Addressable KRAS Mutations through the Structure- and Property-Based Design of Dual-State (GDP/GTP), Reversible Pan-KRAS Inhibitors.

|Mar 27, 2025
Discovery of AMG 193, an MTA-Cooperative PRMT5 Inhibitor for the Treatment of MTAP-Deleted Cancers.

Liping H Pettus, Matthew Bourbeau, Nuria A Tamayo

|Mar 18, 2025
From DNA-Encoded Library Screening to AM-9747: An MTA-Cooperative PRMT5 Inhibitor with Potent Oral In Vivo Efficacy.

Ian Sarvary, Mikkel Vestergaard, Loris Moretti

|Sep 16, 2024
AMG 193, a Clinical Stage MTA-Cooperative PRMT5 Inhibitor, Drives Antitumor Activity Preclinically and in Patients with MTAP-Deleted Cancers.

Brian Belmontes, Katherine K Slemmons, Chun Su

|Mar 14, 2022
Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe.

Nuria A Tamayo, Matthew P Bourbeau, Jennifer R Allen

|Oct 08, 2019
Discovery of AM-6494: A Potent and Orally Efficacious β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2.

Liping H Pettus, Matthew P Bourbeau, Jodi Bradley

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Frequent Collaborators

4 joint publications

Nuria Tamayo

3 joint publications

Katherine K Slemmons

3 joint publications

Ian Sarvary

3 joint publications

Jan Andersson