Jian Zhang

6PUBLICATIONS
10CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and designBiologically active molecules
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Publications (6)

|Sep 09, 2021
Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies.

Boshi Huang, Tiziana Ginex, F Javier Luque

|May 04, 2019
Overview of Recent Strategic Advances in Medicinal Chemistry.

Gaochan Wu, Tong Zhao, Dongwei Kang

|Feb 06, 2019
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles.

Boshi Huang, Wenmin Chen, Tong Zhao

|Jan 10, 2019
Identification of Dihydrofuro[3,4- d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties.

Dongwei Kang, Heng Zhang, Zhao Wang

|Oct 27, 2018
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant.

Jian Zhang, Natarajan Arul Murugan, Ye Tian

|Jul 03, 2018
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.

Jian Zhang, Vasanthanathan Poongavanam, Dongwei Kang

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Frequent Collaborators

6 joint publications

Dongwei Kang

5 joint publications

Peng Zhan

3 joint publications

Vasanthanathan Poongavanam

3 joint publications

Boshi Huang