Christian Mandrycky

8PUBLICATIONS
36CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Respiratory diseasesGene and molecular therapyCell physiologyMedical devices
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Publications (8)

|Sep 15, 2025
Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Sonette Steczina, Saffie Mohran, Matthew C Childers

|Aug 06, 2025
Pressure Points: Endothelial Responses to Shear Stress and Pressure in Health and Pulmonary Arterial Hypertension.

Kellen Hirsch, Christian J Mandrycky, Isabella Kwan

|Jun 04, 2025
Myosin modulator Aficamten inhibits force in cardiac muscle by altering myosin's biochemical activity without changing thick filament structure.

Saffie Mohran, Kristina B Kooiker, Ateeqa Naim

|Sep 20, 2024
Calcium has a direct effect on thick filament activation in porcine myocardium.

Saffie Mohran, Timothy S McMillen, Christian Mandrycky

|Jul 20, 2023
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.

Kristina B Kooiker, Saffie Mohran, Kyrah L Turner

|Feb 13, 2023
Danicamtiv increases myosin recruitment and alters the chemomechanical cross bridge cycle in cardiac muscle.

Kristina B Kooiker, Saffie Mohran, Kyrah L Turner

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