Saffie Mohran

8PUBLICATIONS
47CO-AUTHORS
Cardiology (incl. cardiovascular diseases)Gene and molecular therapyCell physiologyMedical devices
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Publications (8)

|Sep 15, 2025
Molecular mechanisms of altered contraction with the β-myosin R403Q mutation in porcine ventricular muscle and a human stem cell-derived cardiomyocyte model.

Sonette Steczina, Saffie Mohran, Matthew C Childers

|Jun 04, 2025
Myosin modulator Aficamten inhibits force in cardiac muscle by altering myosin's biochemical activity without changing thick filament structure.

Saffie Mohran, Kristina B Kooiker, Ateeqa Naim

|Sep 20, 2024
Calcium has a direct effect on thick filament activation in porcine myocardium.

Saffie Mohran, Timothy S McMillen, Christian Mandrycky

|Jul 31, 2024
Mechanisms of a novel regulatory light chain-dependent cardiac myosin inhibitor.

Kristina Kooiker, Qing-Fen Gan, Ming Yu

|Apr 29, 2024
Incomplete-penetrant hypertrophic cardiomyopathy <i>MYH7</i> G256E mutation causes hypercontractility and elevated mitochondrial respiration.

Soah Lee, Alison S Vander Roest, Cheavar A Blair

|Jul 20, 2023
Danicamtiv Increases Myosin Recruitment and Alters Cross-Bridge Cycling in Cardiac Muscle.

Kristina B Kooiker, Saffie Mohran, Kyrah L Turner

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