James J Beaudoin

13PUBLICATIONS
35CO-AUTHORS
Liquid biopsiesToxicology (incl. clinical toxicology)Pharmaceutical delivery technologiesPredictive and prognostic markersGene and molecular therapy
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Publications (13)

|Jun 22, 2026
Quantitative Systems Toxicology Model Predicts Obeticholic Acid-Associated Liver Injury in Metabolic Dysfunction-Associated Steatotic Liver Disease.

|May 14, 2025
Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione.

Kyunghee Yang, James J Beaudoin, Brett A Howell

|Feb 03, 2025
Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym.

James J Beaudoin, Kyunghee Yang, Brett A Howell

|Sep 24, 2024
Altered bile acid and coproporphyrin-I disposition in patients with autosomal dominant polycystic kidney disease.

Jacqueline B Tiley, James J Beaudoin, Vimal K Derebail

|Jun 10, 2023
The Combination of a Human Biomimetic Liver Microphysiology System with BIOLOGXsym, a Quantitative Systems Toxicology (QST) Modeling Platform for Macromolecules, Provides Mechanistic Understanding of Tocilizumab- and GGF2-Induced Liver Injury.

James J Beaudoin, Lara Clemens, Mark T Miedel

|Apr 16, 2022
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH).

William A Murphy, Jeffry Adiwidjaja, Noora Sjöstedt

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Frequent Collaborators

7 joint publications

Kim L R Brouwer

3 joint publications

William A Murphy

2 joint publications

Jacqueline Bezençon

2 joint publications

Cathy K Gelotte