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Brett A Howell

4PUBLICATIONS

16CO-AUTHORS

Metabolomic chemistryToxicology (incl. clinical toxicology)Pharmaceutical delivery technologiesCancer therapy (excl. chemotherapy and radiation therapy)

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Publications (4)

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|Jan 16, 2026

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant.

Jace C Nielsen, Jeffrey L Woodhead, Brett A Howell

|May 14, 2025

Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione.

Kyunghee Yang, James J Beaudoin, Brett A Howell

|Feb 03, 2025

Modeling and Simulation of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Healthy Adults Using the Quantitative Systems Toxicology Software Platform DILIsym.

James J Beaudoin, Kyunghee Yang, Brett A Howell

|Dec 08, 2023

Quantitative Systems Toxicology Modeling Informed Safe Dose Selection of Emvododstat in Acute Myeloid Leukemia Patients.

Kyunghee Yang, Ronald Kong, Robert Spiegel

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Frequent Collaborators

3 joint publications

Kyunghee Yang

2 joint publications

James J Beaudoin

2 joint publications

Cathy K Gelotte

1 joint publications

Ronald Kong

1 joint publications

John C K Lai

1 joint publications

Evren Atillasoy

1 joint publications

Jace C Nielsen

1 joint publications

Jeffrey L Woodhead

1 joint publications

Lisl K M Shoda

1 joint publications

Dolly A Parasrampuria

Frequent Collaborators

3 joint publications

Kyunghee Yang

2 joint publications

James J Beaudoin

2 joint publications

Cathy K Gelotte

1 joint publications

Ronald Kong

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