Caroline Sychterz
7PUBLICATIONS
8CO-AUTHORS
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Publications (7)
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|Oct 08, 2025
Application of Physiologically Based Pharmacokinetic Modeling to Inform Dose Selection of Mezigdomide in a Phase I Drug-Drug Interaction Study.Joseph Burnett, Caroline Sychterz, Jessica Katz
|Sep 18, 2024
A close examination of BCRP's role in lactation and methods for predicting drug distribution into milk.Caroline Sychterz, Hong Shen, Yueping Zhang
|Nov 25, 2023
The Interplay of Permeability, Metabolism, Transporters, and Dosing in Determining the Dynamics of the Tissue/Plasma Partition Coefficient and Volume of Distribution-A Theoretical Investigation Using Permeability-Limited, Physiologically Based Pharmacokinetic Modeling.Lu Gaohua, Mian Zhang, Caroline Sychterz
|Jul 19, 2023
Physiologically Based Pharmacokinetic Modeling and Simulation of Mavacamten Exposure with Drug-Drug Interactions from CYP Inducers and Inhibitors by CYP2C19 Phenotype.Manting Chiang, Caroline Sychterz, Vidya Perera
|Oct 27, 2022
Performance Verification of CYP2C19 Enzyme Abundance Polymorphism Settings within the Simcyp Simulator v21.Caroline Sychterz, Iain Gardner, Manting Chiang
|Oct 01, 2022
A perspective on the current use of the phase distribution model for predicting milk-to-plasma drug concentration ratio.Mian Zhang, Caroline Sychterz, Ming Chang
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