Lu Gaohua

4PUBLICATIONS
7CO-AUTHORS
Pharmaceutical delivery technologiesClinical pharmacology and therapeuticsSoftware testing, verification and validationToxicology (incl. clinical toxicology)
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Publications (4)

|Aug 07, 2024
Advancements in physiologically based pharmacokinetic modeling for fedratinib: updating dose guidance in the presence of a dual inhibitor of CYP3A4 and CYP2C19.

Ming Chang, Yizhe Chen, Ken Ogasawara

|Nov 25, 2023
The Interplay of Permeability, Metabolism, Transporters, and Dosing in Determining the Dynamics of the Tissue/Plasma Partition Coefficient and Volume of Distribution-A Theoretical Investigation Using Permeability-Limited, Physiologically Based Pharmacokinetic Modeling.

Lu Gaohua, Mian Zhang, Caroline Sychterz

|Oct 27, 2022
Performance Verification of CYP2C19 Enzyme Abundance Polymorphism Settings within the Simcyp Simulator v21.

Caroline Sychterz, Iain Gardner, Manting Chiang

|Jul 13, 2021
Crosstalk of physiological pH and chemical pKa under the umbrella of physiologically based pharmacokinetic modeling of drug absorption, distribution, metabolism, excretion, and toxicity.

Lu Gaohua, Xiusheng Miao, Liu Dou

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Frequent Collaborators

2 joint publications

Caroline Sychterz

1 joint publications

Xiusheng Miao

1 joint publications

Ramakrishna Rachumallu

1 joint publications

Sibylle Neuhoff