Julian Blagg

6PUBLICATIONS
31CO-AUTHORS
Medical infection agents (incl. prions)Cheminformatics and quantitative structure-activity relationshipsMolecular medicineMolecular targetsBiological adaptation
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Publications (6)

|Apr 21, 2026
Pharmacological inhibition of PMS2 induces MMR deficiency and response to immune checkpoint blockade.

|Apr 25, 2019
Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation.

James A H Gilburt, Paul Girvan, Julian Blagg

|Sep 11, 2018
Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4 H-1,2,4-triazol-3-yl)phenyl)-6-methyl- N8-neopentylpyrido[3,4- d]pyrimidine-2,8-diamine (BOS172722).

Hannah L Woodward, Paolo Innocenti, Kwai-Ming J Cheung

|Aug 22, 2018
Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates.

Manjuan Liu, Aurélie Mallinger, Marcello Tortorici

|Jul 13, 2017
Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single-Molecule Spectroscopy.

James A H Gilburt, Hajrah Sarkar, Peter Sheldrake

|Dec 10, 2016
Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases.

Paul A Clarke, Maria-Jesus Ortiz-Ruiz, Robert TePoele

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Frequent Collaborators

2 joint publications

James A H Gilburt

2 joint publications

Liming Ying

2 joint publications

Charlotte A Dodson

1 joint publications

Paul A Clarke