Chengyun Zhang

7PUBLICATIONS
17CO-AUTHORS
Biomolecular modelling and designProteins and peptidesComputational physiologyDeep learning
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Publications (7)

|Jul 13, 2026
HFGuidedDesign: de novo design of cyclic peptide binders via structure-guided discrete diffusion.

|May 31, 2026
HighRes_Builder: improved access and modeling of noncanonical residues for protein structure prediction.

|May 04, 2026
HighFold-MeD2: An Enhanced Boltz-2 Model for Accurate Structure Prediction of N-Methylated and d-Amino Acid Cyclic Peptides.

|Apr 04, 2026
High-PepBinder: A pLM-Guided Latent Diffusion Framework for Affinity-Aware Target-Specific Peptide Design.

Qingyi Mao, Silong Zhai, Sen Cao

|Mar 06, 2026
HighRelax: Physics-Based Refinement of Deep Learning Protein Predictions with Noncanonical Amino Acids.

Sen Cao, Chengyun Zhang, Ning Zhu

|Aug 29, 2025
AlphaFold3 for Noncanonical Cyclic Peptide Modeling: Hierarchical Benchmarking Reveals Accuracy and Practical Guidelines.

Chengyun Zhang, Wentong Wang, Ning Zhu

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Frequent Collaborators

5 joint publications

Jingjing Guo

5 joint publications

Hongliang Duan

3 joint publications

Zhigang Cao

3 joint publications

Qingyi Mao