Chengyun Zhang

9PUBLICATIONS
19CO-AUTHORS
Biomolecular modelling and designProteins and peptidesComputational physiologyDeep learning
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Publications (9)

|Sep 15, 2026
HighFold4: extending AlphaFold3 to accurate cyclic peptide conformation prediction via custom chemical connectivity.

|Sep 10, 2026
HighMorph: De Novo Cyclic Peptide Sequence Design via Protein-Protein Interaction Recapitulation.

|Jul 13, 2026
HFGuidedDesign: de novo design of cyclic peptide binders via structure-guided discrete diffusion.

|May 31, 2026
HighRes_Builder: improved access and modeling of noncanonical residues for protein structure prediction.

|May 04, 2026
HighFold-MeD2: An Enhanced Boltz-2 Model for Accurate Structure Prediction of N-Methylated and d-Amino Acid Cyclic Peptides.

|Apr 04, 2026
High-PepBinder: A pLM-Guided Latent Diffusion Framework for Affinity-Aware Target-Specific Peptide Design.

Qingyi Mao, Silong Zhai, Sen Cao

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Frequent Collaborators

7 joint publications

Jingjing Guo

6 joint publications

Hongliang Duan

5 joint publications

Sen Cao

3 joint publications

Ning Zhu