Sen Cao

7PUBLICATIONS
10CO-AUTHORS
Biomolecular modelling and designComputational physiologyProteins and peptides
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Publications (7)

|Sep 15, 2026
HighFold4: extending AlphaFold3 to accurate cyclic peptide conformation prediction via custom chemical connectivity.

|Sep 10, 2026
HighMorph: De Novo Cyclic Peptide Sequence Design via Protein-Protein Interaction Recapitulation.

|May 04, 2026
HighFold-MeD2: An Enhanced Boltz-2 Model for Accurate Structure Prediction of N-Methylated and d-Amino Acid Cyclic Peptides.

|Apr 04, 2026
High-PepBinder: A pLM-Guided Latent Diffusion Framework for Affinity-Aware Target-Specific Peptide Design.

Qingyi Mao, Silong Zhai, Sen Cao

|Mar 06, 2026
HighRelax: Physics-Based Refinement of Deep Learning Protein Predictions with Noncanonical Amino Acids.

Sen Cao, Chengyun Zhang, Ning Zhu

|Sep 21, 2025
Accurate structure prediction of cyclic peptides containing unnatural amino acids using HighFold3.

Sen Cao, Cheng Zhu, Qingyi Mao

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Frequent Collaborators

7 joint publications

Jingjing Guo

5 joint publications

Chengyun Zhang

4 joint publications

Hongliang Duan

3 joint publications

Ning Zhu