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Rakhi Rajan

11PUBLICATIONS

19CO-AUTHORS

Molecular targetsSynthetic biologyHaematological tumoursProcess control and simulationMicrobial genetics

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Publications (11)

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|Jan 28, 2026

Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation.

Chhandosee Ganguly, Swarmistha Devi Aribam, Alberto Monteiro Dos Santos

|Jul 04, 2025

Structural integrity and side-chain interaction at the loop region of the bridge helix modulate Cas9 substrate discrimination.

Difei Wu, Sydney Snead, Chhandosee Ganguly

|Jan 20, 2025

Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation.

Chhandosee Ganguly, Lindsie Martin, Swarmistha Aribam

|Dec 16, 2024

Exploring CRISPR-Cas9 HNH-Domain-Catalyzed DNA Cleavage Using Accelerated Quantum Mechanical Molecular Mechanical Free Energy Simulation.

Richard Van, Xiaoliang Pan, Saadi Rostami

|Dec 18, 2023

Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage.

Sydney N Newsom, Duen-Shian Wang, Saadi Rostami

|Nov 10, 2021

Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.

Kesavan Babu, Venkatesan Kathiresan, Pratibha Kumari

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Frequent Collaborators

3 joint publications

Peter Z Qin

2 joint publications

Jin Liu

2 joint publications

Sydney Newsom

2 joint publications

Swarmistha Devi Aribam

2 joint publications

Chhandosee Ganguly

1 joint publications

Zhicheng Zuo

1 joint publications

Leonard M Thomas

1 joint publications

Yu-Chieh Wang

1 joint publications

Clarence W Chan

1 joint publications

Alfonso Mondragón

Frequent Collaborators

3 joint publications

Peter Z Qin

2 joint publications

Jin Liu

2 joint publications

Sydney Newsom

2 joint publications

Swarmistha Devi Aribam

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