Rakhi Rajan
11PUBLICATIONS
19CO-AUTHORS
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Publications (11)
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|Jan 28, 2026
Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation.Chhandosee Ganguly, Swarmistha Devi Aribam, Alberto Monteiro Dos Santos
|Jul 04, 2025
Structural integrity and side-chain interaction at the loop region of the bridge helix modulate Cas9 substrate discrimination.Difei Wu, Sydney Snead, Chhandosee Ganguly
|Jan 20, 2025
Helical transition of the bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation.Chhandosee Ganguly, Lindsie Martin, Swarmistha Aribam
|Dec 16, 2024
Exploring CRISPR-Cas9 HNH-Domain-Catalyzed DNA Cleavage Using Accelerated Quantum Mechanical Molecular Mechanical Free Energy Simulation.Richard Van, Xiaoliang Pan, Saadi Rostami
|Dec 18, 2023
Differential Divalent Metal Binding by SpyCas9's RuvC Active Site Contributes to Nonspecific DNA Cleavage.Sydney N Newsom, Duen-Shian Wang, Saadi Rostami
|Nov 10, 2021
Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence.Kesavan Babu, Venkatesan Kathiresan, Pratibha Kumari
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Frequent Collaborators
3 joint publications
Peter Z Qin
2 joint publications
Jin Liu
2 joint publications
Sydney Newsom
2 joint publications
Swarmistha Devi Aribam
2 joint publications
Chhandosee Ganguly
1 joint publications
Zhicheng Zuo
1 joint publications
Leonard M Thomas
1 joint publications
Yu-Chieh Wang
1 joint publications
Clarence W Chan
1 joint publications
Alfonso Mondragón
