Michael DiDonato

4PUBLICATIONS
26CO-AUTHORS
Biomolecular modelling and designApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Nanoscale characterisation
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Publications (4)

|Sep 10, 2026
Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

|Sep 09, 2026
IL-2 mutein-engrafted antibody MHS552 selectively expands functional regulatory T cells in nonclinical models and healthy participants.

|May 19, 2026
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation.

|Jul 19, 2025
Cryo-EM structures of Nipah virus polymerases and high-throughput RdRp assay development enable anti-NiV drug discovery.

Zhenhang Chen, Jeanne Quirit Dudley, Colin Deniston

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Frequent Collaborators

2 joint publications

Dean P Phillips

2 joint publications

Phil B Alper

2 joint publications

Sarah E Kochanek

2 joint publications

Angela Bretz